Critical Care Research Group (CCRG)

Metro North Hospital and Health Service, Queensland Health, Queensland Government

The Critical Care Research Group is one of the largest multidisciplinary critical care research groups in the world. Our clinician-driven research focuses on finding new or improved treatment methods through scientific discovery and improving healthcare outcomes for patients with heart disease, lung disease, sepsis and other critical conditions. CCRG’s world renowned facilities and projects include PRIMELab, Australia’s largest research facility for testing the efficacy and safety of new medical and surgical interventions in large preclinical models, and COVID Critical, an international research collaborative spanning 400+ centres in 64 countries. CCRG has built a reputation around the recruitment and retention of quality researchers and clinicians to improve patient outcomes through scientific discovery.

Website
https://ccrg.org.au/
Organisation type
  • University Research Centre
  • Research Hospital
Number of research staff
20-100 research staff
Address
627 Rode Rd, The Prince Charles Hospital, Chermside QLD 4032

Strengths and capabilities

  • Large preclinical models
  • Large, multi-national research collaborations and projects
  • Biomedical and cardiovascular engineering
  • Extracorporeal membrane oxygenation
  • Pulmonary Diseases and Imaging
  • Sepsis and shock states
  • Computational Fluid Dynamics (CFD)
  • Particle Image Velocimetry (PIV)
  • ICU mental health and delirium
  • Flow cytometry
  • Proteomics
  • Immunoassays
  • Rotation Thromboelastometry (ROTEM®)

Facilities and major equipment

  • Mock heart and blood ex-vivo circulatory loop
  • Preclinical Pulsatile ECMO

Achievements of the centre

  • Recipient, 2023 Vanguard Grant, National Heart Foundation, to test the feasibility of Mitochondrial Transplantation as a supplementary therapy for heart transplantation
  • Recipient, 2024 Vanguard Grant, National Heart Foundation, to test the feasibility of pulsatile bionic pump in an innovative preclinical model of Cardiogenic shock
  • Founders, COVID-19 Critical Care Consortium
  • Founders, ICU of the Future
  • The Living Heart Project – achieved records for furthest distance travelled by donor heart and longest time ‘ex vivo’ – 8 hrs 47 mins

Key science sectors

More information about the sectors this centre is involved in:

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