Centre for Cell Factories and Biopolymers (CCFB)

Griffith Institute for Drug Discovery, Griffith University

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Bioreactor used for manufacture of prototype materials

The Centre for Cell Factories and Biopolymers researches and develops innovative functional materials and technologies that can provide solutions for global health and environmental challenges. We harness the capacity of diverse biological systems to synthesise and assemble biologically active materials by applying bioengineering, synthetic biology and biotechnological approaches. A major research focus of ours is the design and development of innovative bio-based materials for uses as vaccines and in diagnostics. Disease focus areas are bacterial and viral infections such as those caused by Mycobacterium tuberculosis, Pseudomonas aeruginosa, Neisseria meningitidis, Streptococcus pneumoniae, HCV and Dengue. We explore how microorganisms synthesise polymers and assemble biological nano-/micro-structures and investigate the biosynthesis of polysaccharides and biopolyesters. The Centre forms part of the Griffith Institute for Drug Discovery.

Website https://www.griffith.edu.au/institute-drug-discovery/our-institute/cell-factories-biopolymers

Key science sectors

Strengths and capabilities

  • Biomolecular engineering
  • Bioproduction
  • Hybrid biomaterials
  • Biopolymers
  • Vaccines
  • Biotechnology
  • Microbial expression
  • Plant-based expression
  • Bioprocessing
  • Microbiology

Facilities and major equipment

  • Microbial fermentation bioreactor suite
  • Bioprocess development
  • Biomaterials characterization
  • Physical Containment Class 2 (PC2) laboratory
  • Biopolymer analysis unit
  • Protein analysis unit
  • Plant genetic and molecular laboratories
  • Immunology and cell culture laboratories

Number of research staff

Up to 20 research staff

Address

Griffith Institute for Drug Discovery (N75), Don Young Road, Griffith University, Nathan QLD 4111

Lead researchers

  • Professor Bernd Rehm—Developed biomaterials platform technologies for precision-engineering of vaccines, diagnostics, biocatalysts and bioseparation resins.
  • Dr Frank Sainsbury—Developed expression technologies that have supported Phase III clinical trials for VLP vaccines.

Achievements of the centre

Organisation type

  • University Research Centre

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