Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS)

ARC Centre of Excellence for Innovations in Peptide and Protein Science

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Scientist preparing to extract the venom from a funnelweb spider

Headquartered at the University of Queensland, the ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) is a national research centre funded through the Australian Research Council's Centres of Excellence scheme. We work to discover new proteins and peptides from Australia's diverse flora and fauna, decode their biological functions, and develop new proteins and peptides to address challenges in health, agriculture and industry. Together with our industry partners and international collaborators we are working to unleash the power of peptides and proteins for the benefit of humankind. We are developing research and outreach programs to promote peptide and protein science, and are deeply committed to nurturing the next generation of researchers.

Website https://cipps.org.au/

Key science sectors

Strengths and capabilities

  • Peptide and protein chemical synthesis
  • Protein/peptide folding and peptide modifications
  • Medicinal chemistry
  • Organic synthesis
  • Natural product discovery
  • Electrophysiology
  • Recombinant expression
  • NMR spectroscopy and X-ray crystallography
  • Mass spectrometry
  • Proteomics

Facilities and major equipment

  • Clive and Vera Ramaciotti Facility for Production of Drugs in Plants
  • 900MHz, 600MHz, 500MHz NMR spectrometers
  • IMB Microscopy Facility
  • Macromolecular Crystallisation Facilities
  • Cryo-Electron Microscopy Facilities
  • Protein production and flow cytometry
  • Proteomics mass spectrometry facilities
  • Antibody Technology Platform

Number of research staff

100-200 research staff

Address

Queensland Bioscience Precinct, Building 80, 306 Carmody Rd, St Lucia, Brisbane QLD 4067

Lead researchers

  • Professor David Craik—Discovered the cyclotide family of circular proteins and developed ways of synthesising them as stable molecular scaffolds for drug design
  • Professor Glenn King—Translating venoms to drugs with the discovery of Hi1a as novel peptide from the Fraser Island funnel web spider as a treatment for stroke
  • Professor David Fairlie—Drug and target discovery: mimicking proteins and downsizing them to peptides that reproduce the same functions, potencies and specificities

Achievements of the centre

Organisation type

  • Australian Research Centre of Excellence - Headquarters

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